Joshua Roffman, M.D., MSc.
Co-Director, Mass General Neuroscience
Director of Clinical Neuroscience Research and Training for the MGH Department of Psychiatry
Co-Director, MGH Division of Psychiatric Neuroimaging
Read about Dr. Roffman's lab: http://roffmanlab.mgh.harvard.edu/
Publications
Roffman JL, Gollub RL, Calhoun VD, Wassink TH, Weiss AP, Ho BC, White T, Clark VP, Fries J, Andreasen NC, Goff DC, Manoach DS. MTHFR 677C>T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val>Met. Proc Natl Acad Sci USA 105:17573-17578, 2008. PMCID: PMC2582272
Roffman JL, Lamberti JS, Achtyes E, Macklin EA, Galendez GC, Raeke LH, Silverstein NJ, Smoller JW, Hill M, Goff DC. Randomized multi-center investigation of folate plus vitamin B12 supplementation in schizophrenia. JAMA Psychiatry 70:481-489, 2013. PMCID: PMC4394629
Roffman JL, Tanner AS, Eryilmaz H, Rodriguez-Thompson A, Silverstein NJ, Ho NF, Nitenson AZ, Chonde DB, Greve DN, Abi-Dargham A, Buckner RL, Manoach DS, Rosen BR, Hooker JM, Catana C. Dopamine D1 signaling organizes network dynamics underlying working memory. Science Advances, 2: e1501672, 2016. PMCID: PMC4928887
Roffman JL, Petruzzi LJ, Brown HE, Eryilmaz H, Ho NF, Giegold M, Silverstein NJ, Bottiglieri T, Manoach DS, Smoller JW, Henderson DC, Goff DC. PMCID in progress. Biochemical, physiological, and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial. Mol Psychiatry, 23:316-322, 2018. PMCID: PMC5599314
Eryilmaz H, Dowling KF, Huntington FC, Rodriguez-Thompson A, Soare TW, Beard LM, Lee H, Blossom JC, Gollub RL, Susser E, Gur RC, Calkins ME, Gur RE, Satterthwaite TD, Roffman JL. Association of prenatal exposure to population-wide folic acid fortification with altered cerebral cortex maturation in youths. JAMA Psychiatry,75:918-28, 2018. PMCID: PMC6142921