Apr
17
to Apr 19

Sexual Dimorphism in Cancer - Hybrid Conference (Lausanne, Switzerland) 🇨🇭

Our Swiss Partner CancerPrev, led by Dr Gian Paolo Dotto, is organizing a 3-day hybrid conference in Lausanne on April 17-19th focusing on the impact of sex hormones and chromosomes on cancer susceptibility, with an emphasis on (epi)genetics, sex hormones, cancer cell biology, metabolism and the immune system.

Registration are open until February 29th.

More details on the program, speakers and the registration fee here: https://cancerprev.ch/conference-sd-cancer-2024/

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Apr
5
12:00 PM12:00

April 19th - Open CEC Seminar

Dr Julia Sacher (Max Planck Institute, Germany) is visiting our Center on April 19th and we are organizing a Seminar for MGH-MGB Faculty at 1pm. Dr Sacher is a Professor of Cognitive Neuroendocrinology with the Medical Faculty of the University Clinic of Leipzig and the Max Planck Institute for Human Brain Sciences.

The event will be at CNY Room (2.204) and online. It would be a wonderful opportunity for many and we wanted to share her perspectives and experience.

Seminar Details: Topic: “A focus on hormonal transitions across the female lifespan: Implications for Brain Health and Individual Ageing Trajectories" Date: Friday, April 19th Time: 1:00 PM - 2:30 PM EST Location: CNY Brain Map room (2.204) and over zoom Guest Speaker: Dr. Julia Sacher

Should you have any questions or require further information, please do not hesitate to contact me (jherve@mgh.harvard.edu). We are looking forward to seeing many of you there.

Guest Speaker Biography: Dr. Julia Sacher is a professor of Cognitive Neuroendocrinology with the Medical Faculty of the University Clinic of Leipzig and the Max Planck Institute for Human Brain Sciences. She is also a faculty member of the Max Planck School of Cognition (https://cognition.maxplanckschools.org/en), the International Max Planck Research School of Cognitive Neuroimaging, and the Berlin School of Mind & Brain.

Dr. Sacher’s original training is as a psychiatrist and a neuroscientist. She obtained her MD-degree in Vienna. Her PhD in neuroscience (Medical University Vienna, Austria) was followed by a postdoctoral clinical and research fellowship at the Centre for Addiction & Mental Health (CAMH), University of Toronto, research stays at University of Pittsburgh and Carnegie Mellon University (funded by the NIH), and CDI (Career Development Institute for Mental Health Research) training at the University of Pittsburgh and Stanford University, funded by the NIH. Dr. Sacher is a distinguished university scholar and has held several prestigious Awards and Fellowships, such as the Alexander von Humboldt Fellowship, the Brain and Behavior Young Investigator Award (2x), the CINP Rafaelsen Award, and the Branco Weiss Fellowship at the Society in Science (ETH, Zurich). She is a full member of the American College of Neuropsychopharmaoclogy (ACNP) and serves on advisory boards, editorial boards, and peer review panels internationally and nationally, including CAMH’s Womenmind Seed Funding Competition. Dr. Sacher drives initiatives in women's health research by advocating precision-imaging for hormonal transitions like the menstrual cycle, pregnancy, and menopause, and encourages the integration of sex and gender-based analyses in neuroscience to uplift mental health for both women and men.

Dr. Sacher’s discoveries include: --first evidence for neurochemical changes in humans during major hormonal transition phases, such as increases of MAO-A in early postpartum, perimenopause and postpartum depression (Arch Gen Psch/JAMA Psych 2010, 2011; Neuropsychopharmacology, 2015), --serotonin transporter dynamics in premenstrual dysphoric disorder (Biol Psychiatry 2023) --proof of concept for dense sampling of ovarian hormones and human brain architecture including first human evidence of hippocampal subfield dynamics using high-field 7T MRI (Front Neurosci 2015; Nature Mental Health 2023) --pioneering sex as a discovery variable in multimodal large neuroimaging data-banks, such as in the relationship between obesity, brain health and cognitive performance across the life-span (JAMA Netw Open 2019) --first evidence for association between maternal mood postpartum and infant language development (JAMA Netw Open 2021) --prioritizing diversity, sex, and gender in the application of artificial intelligence (AI) for big multi-organ MR data-bases, such as the UK Biobank and the Human Connectome Project (Science 2023)

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Mar
1
6:00 AM06:00

Congratulations to Dr Zsido !

Congratulations to ICON-✘ Junior Faculty Dr Rachel Zsido, who has been awarded the prestigious Otto Hahn Medal. Since 1978, the Max Planck Society (Munich, Germany) has awarded the Otto Hahn Medal to young researchers for outstanding scientific achievements.

Dr. Zsido her Ph.D. in Cognitive Neuroscience at the Max Planck Institute for Human Cognitive and Brain Sciences. During her doctoral studies, she used multimodal neuroimaging techniques (MRI, EEG, PET) to investigate how sex steroids shape brain structure, function, and chemistry across the lifespan; with emphasis on women’s increased risk for depression and dementia.

We are really proud to have Dr Zsido in our team, advancing Sex Selective Research and Medicine.

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Feb
20
to Feb 21

$100 Million to address critical gaps in Women's Health in the Sprint for Women's Health Program (ARPA-H)

ICON-X founder and Executive Director, Dr Jill Goldstein, was honored to have been part of an extraordinary gathering yesterday, marking a pivotal moment in Women's Health Research. The announcement of $100 million in funding for Advanced Research Projects Agency for Health (ARPA-H)'s inaugural Sprint for Women’s Health, led by Dr. Jill Biden, is a testament to the power of collaboration, innovation, and sheer will power to bring this initiative forward to put women's health issues front and center in the conversation at the highest level of government.

Yesterday was filled with inspiration as I brainstormed alongside remarkable minds from Research/Academia, Femtech, Entrepreneurs, Women's Health Investors and Advocates.

For decades, and more recently with the 2018 launch of the Innovation Center on Sex Differences in Medicine (ICON-✘) at MGH, we have been advocating with our colleagues to not only enhance discoveries around sexdifferences/women's health in medicine but to translate them into what we call sex-selective diagnostictools and therapies. This ARPA-H women's health initiative will allow for the realization of that mission on a broad scale.

Witnessing FLOTUS, Dr. Jill Biden, spearhead this initiative fills us with hope and excitement to help move it forward successfully. This endeavor is set to transform the lives of countless women in America and beyond. Together, we will pave the way for a healthier, more equitable future and the realization of precision medicine.

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May
26
1:00 PM13:00

Announcement : A new alliance with the Colombian Ministry of Science 🇨🇴 & MGH Psychiatry

Really happy to announce the signing of a memorandum of understanding between the MGH Department of Psychiatry and the Colombian Ministry of Science that will allow us to advance collaborative efforts in mental health research in Colombia. A first concrete steps towards a neuromodulation and neuropsychiatry network in Colombia and Latin America.

We are looking forward to working with incredible scientists on this initiative led by ICON-X colleagues: Drs Ronald Garcia, Yakeel Quiroz, Roy Perlis and Jill Goldstein.

Full article (Spanish) : https://minciencias.gov.co/sala_de_prensa/minciencias-consolida-nueva-alianza-con-el-hospital-general-massachusetts

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Apr
3
12:30 PM12:30

Congratulations to Dr Joshua Roffman

We are pleased to announce that Dr. Joshua Roffman will serve as the Director of Clinical Neuroscience Research and Training for the Mass General Department of Psychiatry. In this new leadership role, Dr. Roffman will work closely with Dr. Deborah Blacker, Associate Chief for Research, to oversee the department’s clinical and translational research that occurs at the Charlestown Navy Yard campus of MGH.

Dr. Roffman has previously served as co-director of the Division of Psychiatric Neuroimaging with Dr. Randy Buckner, who will continue in this role, as well as the inaugural Psychiatry co-director of Mass General Neuroscience.

This new role builds on Dr. Roffman’s many years of service providing formal and informal mentorship of early career trainees, including as founding co-director of the Translational Neuroscience Training for Clinicians T32 fellowship. In addition to overseeing research infrastructure and space allocation at CNY, Dr. Roffman will advise and advocate for investigators at all career levels, facilitate both research collaboration and community-building, and work with departmental leadership to strengthen and diversify our pipeline of early career investigators.

Dr Roffman serves as our Career Enhancement Core MGH site PI for our SCORE. https://www.icon.mgh.harvard.edu/score-cec

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Jan
13
4:00 PM16:00

CancerPrev - 2023 Seminars

Dr Dotto's team at the Cancerprev are organizing online seminars, which they recently started with their first speaker Prof. Dr. Simona Cristea.

The next seminar will take place on January Friday 13th, 2023 at 4 pm (GMT +1) by Prof. Dr. Monica Dentice from the Dept. of Clinical Medicine and Surgery, University of Naples Federico II.

Talk : “The intracellular modulation of thyroid hormone affects the tumor-stroma cross talk in non melanoma skin cancer”

The seminar schedule will be regularly updated on their webpage: https://cancerprev.ch/icpi-seminars/

You can also follow iCPI on LinkedIn where they will announce upcoming seminars: https://cancerprev.ch/icpi-seminars/

Dial in for the meeting: Topic: iCPI Seminar: Prof. Monica Dentice Time: Jan 13, 2023 04:00 PM Amsterdam, Berlin, Rome, Stockholm, Vienna

      Join Zoom Meeting       https://unil.zoom.us/j/5494789983

      Meeting ID: 549 478 9983       Password: 638738

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Sep
9
8:00 AM08:00

(Online Course) Multiple Sclerosis Comprehensive Update: Overview of Clinical Management, Therapeutic Strategies and Research Trends

Drs Houtchens, Klawiter & ICON-✘ Faculty, Dr Tanuja Chitnis’ upcoming online course on Multiple Sclerosis.

More on Dr Chitnis

This CME program offered through Harvard Medical School will present the most up-to-date clinical and research information relevant to health care providers who treat patients with multiple sclerosis. Through this initiative, participants will advance their knowledge and competence to provide excellent clinical care to patients with MS and will thoroughly improve their understanding of the recent and important research trends and results in this rapidly developing field.

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Jun
6
9:00 AM09:00

AJP-Heart and Circulatory Physiology Podcast (Dr Hale & Lakshmi Madhavpeddi, University of Arizona))

Topic: Prenatal Dexamethasone Alters Female Cardiovascular Function

Dr Taben Hale, Lakshmi Madhavpeddi (University of Arizona, Phoenix)

How does in utero glucocorticoid administration impact autonomic control of the heart in adult offspring in a sex-dependent manner? In this episode, Associate Editor Dr. Crystal Ripplinger (University of California – Davis) interviews authors Dr. Taben Hale and Lakshmi Madhavpeddi (University of Arizona) along with expert Dr. Glen Pyle (University of Guelph) about the new work by Madhavpeddi et al.

https://ajpheart.podbean.com/e/prenatal-dexamethasone-alters-female-cardiovascular-function/

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Mar
31
9:30 AM09:30

Tech4Eva Summit : “Equality and Gender Differences - Why Femtech matters"

Tech4Eva Summit – March 31st, 2022

The 2nd Opening Ceremony of Tech4Eva was organized virtually and at the Rolex Learning Center at EPFL (Lausanne, Switzerland) to accelerate and disrupt Women's health across the world. The event brought together the ecosystem including 250+ experts, ecosystem builders, investors, corporates, researchers, entrepreneurs, and innovators to co-create new solutions and to launch initiatives for better health for all, and for gender equity in health research.

Keynote : keynote on the Impact of Sex on Risk & Therapeutics for Chronic Disease.

https://www.tech4eva.ch/event/tech4eva-opening-ceremony-2022

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Mar
13
9:00 AM09:00

(Article) Novel form of vagus nerve stimulation promising for treatment of major depressive disorder - Dr Ronald Garcia

Novel form of vagus nerve stimulation promising for treatment of major depressive disorder

The vagus nerve, as the main component driving the parasympathetic nervous system, is involved in regulating mood. Implanting electrodes to stimulate the vagus nerve in the neck can be useful in managing treatment-resistant major depressive disorder (MDD), but significant side effects and surgical morbidity are possible.

https://advances.massgeneral.org/neuro/journal.aspx?id=2155

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Jan
25
11:30 AM11:30

Dr. Goldstein author of Introduction and Editorial in Psychiatric Annals Vol. 52 No. 1

"Women are central to the solutions to one of the primary causes of disability worldwide- the co-occurrence of depression and heart disease - given they have twice the risk of men, resulting in 3-5 fold increase of death from heart disease. Developing sex-dependent therapies at the brain-cardiac interface will be critical to tackling this crisis." -Dr. Jill Goldstein Ph.D.

Find the editorial article here: https://journals.healio.com/doi/10.3928/00485713-20211227-01

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Dec
13
8:00 AM08:00

Dr. Jill Goldstein newly elected MGH Executive Committee On Research (ECOR) Representative

A total of 331 faculty members cast their ballots to select two new elected representatives to ECOR. The two new elected representatives are:

Jill Goldstein, PhD Professor Psychiatry / Medicine Innovation Center on Sex Differences in Medicine

Jocelyn Carter, MD, MPH Assistant Professor Medicine Division of Internal Medicine

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